Lydon, Nicholas B: search on Z-Library

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1

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells

Tamura, Shu, Buchdunger, Elisabeth, Ohno, Sayuri, Segal, Gerald M., Fanning, Shane, Zimmermann, Jürg, Lydon, Nicholas B., Druker, Brian J.

Journal:

Nature Medicine

Year:

1996

File:

PDF, 617 KB

1996

2

ChemInform Abstract: The Structure-Based Design of ATP-Site Directed Protein Kinase Inhibitors

Leticia M. Toledo, Nicholas B. Lydon, Daniel Elbaum

Journal:

Year:

1999

File:

PDF, 24 KB

1999

3

Wrinkles Riding Waves in Soft Layered Materials

Abi Ghanem, Maroun, Liang, Xudong, Lydon, Brittany, Potocsnak, Liam, Wehr, Thorsen, Ghanem, Mohamed, Hoang, Samantha, Cai, Shengqiang, Boechler, Nicholas

Journal:

Advanced Materials Interfaces

Year:

2018

Language:

english

File:

PDF, 1.42 MB

english, 2018

4

Use of a Pharmacophore Model for the Design of EGF-R Tyrosine Kinase Inhibitors: 4-(Phenylamino)pyrazolo[3,4- d ]pyrimidines

Traxler, Peter, Bold, Guido, Frei, Joerg, Lang, Marc, Lydon, Nicholas, Mett, Helmut, Buchdunger, Elisabeth, Meyer, Thomas, Mueller, Marcel, Furet, Pascal

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 387 KB

english, 1997

5

Cellular and In Vivo characterization of the MCR rat mammary tumor model

Alois Gutzwiller, Urs Regenass, Alex Matter, Nicholas B. Lydon

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 914 KB

english, 1993

6

The angiotensin AT2 receptor stimulates protein tyrosine phosphatase activity and mediates inhibition of particulate guanylate cyclase

Serge P. Bottari, Isabelle N. King, Serge Reichlin, Ilse Dahlstroem, Nicholas Lydon, Marc de Gasparo

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 852 KB

english, 1992

7

Inhibition of Epidermal Growth Factor-Mediated ERK1/2 Activation by in Situ Electroporation of Nonpermeant [(alkylamino)methyl]Acrylophenone Derivatives

BROWNELL, HEATHER L., LYDON, NICHOLAS B., SCHAEFER, ERIK, ROBERTS, THOMAS M., RAPTIS, LEDA

Journal:

DNA and Cell Biology

Year:

1998

Language:

english

File:

PDF, 13.05 MB

english, 1998

8

Structures of staurosporine bound to CDK2 and cAPK – new tools for structure-based design of protein kinase inhibitors

Leticia M Toledo, Nicholas B Lydon

Journal:

Year:

1997

Language:

english

File:

PDF, 1.30 MB

english, 1997

9

Synthesis of ferrocene-functionalized monomers for biodegradable polymer formation

Upton, Brianna M., Gipson, Raymond M., Duhović, Selma, Lydon, Brian R., Matsumoto, Nicholas M., Maynard, Heather D., Diaconescu, Paula L.

Journal:

Inorganic Chemistry Frontiers

Year:

2014

Language:

english

File:

PDF, 525 KB

english, 2014

10

Activation of adenylate cyclase in bovine corpus-luteum membranes by human choriogonadotropin, guanine nucleotides and NaF

Lydon, Nicholas B., Young, John L., Stansfield, David A.

Journal:

Biochemical Journal

Year:

1981

Language:

english

File:

PDF, 1.20 MB

english, 1981

11

Paeciloquinones A,B,C,D,E and F: New Potent Inhibitors of Protein Tyrosine Kinases Produced by Paecilomyces carneus. I. Taxonomy, Fermentation, Isolation and Biological Activity.

PETERSEN, FRANK, FREDENHAGEN, ANDREAS, METT, HELMUT, LYDON, NICHOLAS B., DELMENDO, RON, JENNY, HANS-BEAT, PETER, HEINRICH H.

Journal:

The Journal of Antibiotics

Year:

1995

Language:

english

File:

PDF, 552 KB

english, 1995

12

715 CABAZITAXEL FOR METASTATIC CASTRATION RESISTANT PROSTATE CANCER (MCRPC): FINAL QUALITY OF LIFE (QOL) RESULTS WITH SAFETY DATA FROM THE UNITED KINGDOM (UK) EARLY ACCESS PROGRAMME (EAP) (NCT01254279)

Bahl, Amit, Masson, Susan, Malik, Zafar, Birtle, Alison, Sundar, Santhanam, Jones, Robert, James, Nicholas, Mason, Malcolm, Bottomley, David, Lydon, Anna, Chowdhury, Simon, Wylie, James, De Bono, Joha

Journal:

The Journal of Urology

Year:

2013

Language:

english

File:

PDF, 47 KB

english, 2013

13

Sulfonylbenzoyl-nitrostyrenes: Potential bisubstrate type inhibitors of the EGF-receptor tyrosine protein kinase

Traxler, Peter M., Wacker, Oskar, Bach, Ha L., Geissler, Johanna F., Kump, Wilhelm, Meyer, Thomas, Regenass, Urs, Roesel, Johannes L., Lydon, Nicholas

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 3.43 MB

english, 1991

14

Wrinkles: Wrinkles Riding Waves in Soft Layered Materials (Adv. Mater. Interfaces 1/2019)

Abi Ghanem, Maroun, Liang, Xudong, Lydon, Brittany, Potocsnak, Liam, Wehr, Thorsen, Ghanem, Mohamed, Hoang, Samantha, Cai, Shengqiang, Boechler, Nicholas

Journal:

Advanced Materials Interfaces

Year:

2019

File:

PDF, 2.03 MB

2019

15

Hormonal Activation of Bovine Luteal Adenylate Cyclase

LYDON, NICHOLAS B., YOUNG, JOHN L., STANSFIELD, DAVID A.

Journal:

Biochemical Society Transactions

Year:

1979

File:

PDF, 213 KB

1979

16

Phenylamino-pyrimidine (PAP) — derivatives: a new class of potent and highly selective PDGF-receptor autophosphorylation inhibitors

Jürg Zimmermann, Elisabeth Buchdunger, Helmut Mett, Thomas Meyer, Nicholas B. Lydon, Peter Traxler

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 316 KB

english, 1996

17

4,5-Dianilinophthalimide: A Protein-Tyrosine Kinase Inhibitor with Selectivity for the Epidermal Growth Factor Receptor Signal Transduction Pathway and Potent in vivo Antitumor Activity

Elisabeth Buchdunger, Uwe Trinks, Helmut Mett, Urs Regenass, Marcel Muller, Thomas Meyer, Elaine McGlynn, Lorenzo A. Pinna, Peter Traxler and Nicholas B. Lydon

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.16 MB

english, 1994

18

Impact of BRAF Mutation Class on Disease Characteristics and Clinical Outcomes in BRAF-Mutant Lung Cancer

Dagogo-Jack, Ibiayi, Martinez, Pablo, Yeap, Beow Y., Ambrogio, Chiara, Ferris, Lorin A, Lydon, Christine, Nguyen, Tom, Jessop, Nicholas A., Iafrate, A. John, Johnson, Bruce E., Lennerz, Jochen K., Sha

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 1.40 MB

english, 2018

19

[(Alkylamino)methyl]acrylophenones: Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase

Traxler, Peter, Trinks, Uwe, Buchdunger, Elisabeth, Mett, Helmut, Meyer, Thomas, Mueller, Marcel, Regenass, Urs, Roesel, Johannes, Lydon, Nicholas

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.05 MB

english, 1995

20

Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic myelogenous leukemia

Druker, Brian J, Lydon, Nicholas B, Kaelin, William G

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

21

A strategy for screening anti-tumor drugs utilizing oncogenes encoded in retroviral vectors

Michael J. Corbley, Van Cherington, Peter M. Traxler, Nicholas B. Lydon, Thomas M. Roberts

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 896 KB

english, 1996

22

Modelling study of protein kinase inhibitors: Binding mode of staurosporine and origin of the selectivity of CGP 52411

Pascal Furet, Giorgio Caravatti, Nicholas Lydon, John P. Priestle, Janusz M. Sowadski, Uwe Trinks, Peter Traxler

Journal:

Journal of Computer-Aided Molecular Design

Year:

1995

Language:

english

File:

PDF, 826 KB

english, 1995

23

Lessons learned from the development of imatinib

Nicholas B Lydon, Brian J Druker

Journal:

Leukemia Research

Year:

2004

Language:

english

File:

PDF, 414 KB

english, 2004

24

Selective Inhibition of the Platelet-Derived Growth Factor Signal Transduction Pathway by a Protein-Tyrosine Kinase Inhibitor of the 2- Phenylaminopyrimidine Class

Elisabeth Buchdunger, Jurg Zimmermann, Helmut Mett, Thomas Meyer, Marcel Muller, Urs Regenass and Nicholas B. Lydon

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.13 MB

english, 1995

25

Attacking cancer at its foundation

Lydon, Nicholas

Journal:

Nature Medicine

Year:

2009

Language:

english

File:

PDF, 837 KB

english, 2009

26

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

Druker, Brian J., Talpaz, Moshe, Resta, Debra J., Peng, Bin, Buchdunger, Elisabeth, Ford, John M., Lydon, Nicholas B., Kantarjian, Hagop, Capdeville, Renaud, Ohno-Jones, Sayuri, Sawyers, Charles L.

Journal:

Boston Medical and Surgical Journal

Year:

2001

Language:

english

File:

PDF, 177 KB

english, 2001

27

CGP 57148, a Tyrosine Kinase Inhibitor, Inhibits the Growth of Cells Expressing BCR-ABL, TEL-ABL, and TEL-PDGFR Fusion Proteins

Carroll, Martin, Ohno-Jones, Sayuri, Tamura, Shu, Buchdunger, Elisabeth, Zimmermann, JuÌrg, Lydon, Nicholas B., Gilliland, D. Gary, Druker, Brian J.

Journal:

Year:

1997

File:

PDF, 258 KB

1997

28

A potent protein-tyrosine kinase inhibitor which selectively blocks proliferation of epidermal growth factor receptor-expressing tumor cells in vitro and in vivo

Nicholas B. Lydon, Helmut Mett, Marcel Mueller, Michael Becker, Robert M. Cozens, David Stover, Daren Daniels, Peter Traxler, Elisabeth Buchdunger

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 243 KB

english, 1998

29

Hormonal Activation of Bovine Luteal Adenylate Cyclase

LYDON, NICHOLAS B., YOUNG, JOHN L., STANSFIELD, DAVID A.

Journal:

Biochemical Society Transactions

Year:

1979

Language:

english

File:

PDF, 213 KB

english, 1979

30

Final quality of life and safety data for patients with metastatic castration-resistant prostate cancer treated with cabazitaxel in the UK Early Access Programme (EAP) (NCT01254279)

Bahl, Amit, Masson, Susan, Malik, Zafar, Birtle, Alison J., Sundar, Santhanam, Jones, Rob J., James, Nicholas D., Mason, Malcolm D., Kumar, Satish, Bottomley, David, Lydon, Anna, Chowdhury, Simon, Wyl

Journal:

BJU International

Year:

2015

Language:

english

File:

PDF, 354 KB

english, 2015

31

The Tyrosine Kinase Inhibitor CGP57148B Selectively Inhibits the Growth of BCR-ABLâPositive Cells

Deininger, Michael W.N., Goldman, John M., Lydon, Nicholas, Melo, Junia V.

Journal:

Year:

1997

File:

PDF, 360 KB

1997

32

Phenylamino-Pyrimidine (PAP) Derivatives: A New Class of Potent and Selective Inhibitors of Protein Kinase C (PKC)

Jürg Zimmermann, Giorgio Caravatti, Helmut Mett, Thomas Meyer, Marcel Müller, Nicholas B. Lydon, Doriano Fabbro

Journal:

Archiv der Pharmazie

Year:

1996

Language:

english

File:

PDF, 589 KB

english, 1996

33

Hybrid Zeolitic Imidazolate Frameworks: Controlling Framework Porosity and Functionality by Mixed-Linker Synthesis

Thompson, Joshua A., Blad, Catherine R., Brunelli, Nicholas A., Lydon, Megan E., Lively, Ryan P., Jones, Christopher W., Nair, Sankar

Journal:

Chemistry of Materials

Year:

2012

Language:

english

File:

PDF, 485 KB

english, 2012

34

4-(Phenylamino)pyrrolopyrimidines: Potent and Selective, ATP Site Directed Inhibitors of the EGF-Receptor Protein Tyrosine Kinase

Traxler, Peter M., Furet, Pascal, Mett, Helmut, Buchdunger, Elisabeth, Meyer, Thomas, Lydon, Nicholas

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 274 KB

english, 1996

35

Potent and selective inhibitors of the Abl-kinase: phenylamino-pyrimidine (PAP) derivatives

Jürg Zimmermann, Elisabeth Buchdunger, Helmut Mett, Thomas Meyer, Nicholas B. Lydon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 279 KB

english, 1997

36

Large-scale purification and characterisation of a recombinant epidermal growth-factor receptor protein-tyrosine kinase : Modulation of activity by multiple factors

Elaine McGLYNN, Michael BECKER, Helmut METT, Sarah REUTENER, Robert COZENS, Nicholas B. LYDON

Journal:

Year:

1992

Language:

english

File:

PDF, 1.23 MB

english, 1992

37

Activation of bovine luteal adenylate cyclase by human choriogonadotropin in vitro : persistence of the activated state following preactivation and washing

LYDON, NICHOLAS B., YOUNG, JOHN L., STANSFIELD, DAVID A.

Journal:

Biochemical Society Transactions

Year:

1980

Language:

english

File:

PDF, 236 KB

english, 1980

38

Immunochemical mapping of .alpha.-2 interferon

Lydon, Nicholas B., Favre, Catherine, Bove, Sylvie, Neyret, Odile, Benureau, Sylvie, Levine, Alan M., Seelig, Gail F., Nagabhushan, Tatanahalli L., Trotta, Paul P.

Journal:

Year:

1985

Language:

english

File:

PDF, 2.02 MB

english, 1985

39

The effect of dimethyl 3,3′-dithiobispropionimidate on the adenylate cyclase activity of bovine corpus luteum: stimulation of particulate enzyme activity and the stabilization of activity to dispersion in detergent

YOUNG, JOHN L., LYDON, NICHOLAS B., STANSFIELD, DAVID A.

Journal:

Biochemical Society Transactions

Year:

1980

Language:

english

File:

PDF, 246 KB

english, 1980

40

Evidence for SH3 domain directed binding and phosphorylation of Sam68 by Src

Shen, Zhiwei, Batzer, Andreas, Koehler, Jackie A, Polakis, Paul, Schlessinger, Joseph, Lydon, Nicholas B, Moran, Michael F

Journal:

Year:

1999

Language:

english

File:

PDF, 303 KB

english, 1999

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